Climate change may represent one of the most disruptive forces in the contemporary era shaping our environment and, ultimately, questioning the way humanity has approached the use and abuse of resources. Despite the vast amount of literature in climate change produced from both natural and social sciences, efforts in coming to terms with climate change from a multi-discipline perspective are needed. In this webinar, we presented a discussion on climate change from three scientific lenses: (i) The perceptions of Amazonian indigenous communities on climate change, (ii) Climate variability at different time-scales using different novel tools to interpret changes in terrestrial ecosystems, and (iii) How social sciences are needed for a more comprehensive understanding of global environmental change.