Gender: Female
Weapon Steel Fans

Family:
- Jerrod (father; deceased)
- Sindel (mother)
- Shao Kahn (stepfather)
- Mileena (clone sister)
Origin: Edenia

Fighting styles: Ba Gua

Kitana first appears in Mortal Kombat II as a member of the Edenian race in from the fictional dimension, Outworld. While she is thousands of years old, she more closely resembles a young woman. For most of her life, Kitana believed she was the daughter of Shao Kahn and Queen Sindel. She served as the former's personal elite assassin for centuries, working alongside her sister Mileena and her best friend Jade. Eventually, she found out the truth; Shao Kahn murdered her true father King Jerrod, usurped his throne, and claimed Sindel as his wife to rule over Edenia. He placed Kitana under a spell to make her his loyal daughter and assassin, and had his subordinate Shang Tsung create a disfigured clone of her to be a backup heir. That clone, Mileena, would spy on Kitana and kill and replace her if she ever rose against Shao Kahn. Realizing her life had been a lie, Kitana turned against Shao Kahn and began fighting alongside Earthrealm's champions to defeat the evil emperor and free her home realm of his tyranny.[11] At this point, Kitana started developing a romantic interest in Earthrealm champion Liu Kang. She also came to hate Mileena for being a reminder of the lie she lived and her existing only to kill her.According to the semi-canonical spin-off game Mortal Kombat: Shaolin Monks (2005), after Kitana was found to be no longer loyal to Shao Kahn, she was placed into a spell-induced trance and forced to fight the Earthrealm heroes, Mileena, and Jade before being freed by the Shaolin warrior monks Liu Kang and Kung Lao. Eventually, the sisters clash and Kitana slays Mileena.

In the rebooted timeline of Mortal Kombat, which retells the events of the first three Mortal Kombat games, she and Jade are sent by Shao Kahn to compete in a Mortal Kombat tournament. Kitana battles Liu Kang in an attempt to ensure that he will not reach the final stages of the first tournament, but is defeated. Expecting to die, she is surprised by his decision to spare her. Later, during the second tournament, Kitana is approached by Raiden, who informs her that her supposed past as Shao Kahn's daughter is a lie. Plagued by doubts, she infiltrated Shang Tsung's flesh pits and discovered the newly-created Mileena. Before the Kahn, she accuses Shang Tsung of attempting to replace her, but is shocked to learn that the Emperor himself ordered Mileena's creation. He imprisoned Kitana in the palace, prior to an execution, and commands his "true daughter" to be brought to him. Kitana is soon freed by Liu Kang, and she and Jade escape to Earthrealm to join their new allies against Outworld's forces. They assist in the battle for Earthrealm, but are killed alongside several other warriors by Kitana's corrupted mother, Sindel. In the end, she is shown to be one of the warriors that were resurrected by Quan Chi in the Netherrealm to battle Raiden.

In Mortal Kombat X (2015) Kitana returns as one of Quan Chi's revenants. She fought Jax and Cassie Cage in the game's story mode. Following Quan Chi's death and Shinnok's defeat, she and fellow revenant Liu Kang became the Netherrealm's new rulers.

IKitana's revenant aligned herself with the keeper of time Kronika after the latter promised her a timeline without Raiden. As a result of Kronika's actions however, a past version of Kitana and Liu Kang were brought to the present. While he traveled to Earthrealm to find out more about what happened, she stayed in Outworld to find Shao Kahn, who had also been brought to the present.To aid the new Outworld emperor Kotal Kahn, Kitana forged alliances with Outworld's disparate factions before leading them into battle against Shao Kahn; personally defeating and maiming him herself. Kotal, who had been crippled during the fight, appointed Kitana the new Kahn of Outworld in recognition of her skills in combat and diplomacy. After Kronika kidnaps Liu Kang, Kitana and her Outworld army aided Earthrealm's allied forces against Kronika's army until Raiden merged with Liu Kang's past self and his revenant to become Fire God Liu Kang.As the rest of her allies fought off Kronika's forces, Kitana joined Liu Kang in breaching Kronika's keep. However, Kronika reverses time for everyone except Liu Kang, who faces her and his allies' revenants alone. In one of the game's endings, Liu Kang defeats Kronika and is able to bring Kitana back to help him forge a new timeline. In the DLC story expansion Aftermath, Kitana was reunited with Sindel after a time-traveling Shang Tsung and Fujin resurrected her to help in the fight against Kronika. However, she was horrified to learn of her mother's true megalomaniacal nature when she failed to stop her from betraying Earthrealm and Outworld.