Sen. Kamala Harris will accept her party’s nomination for vice president on Wednesday night, in a history-making address during the third night of the 2020 Democratic National Convention.

In doing so, the 55-year-old Californian will become the first Black woman, as well as the first woman of Indian descent, to appear on a major party ticket. Her nomination is just the latest in a number of “firsts” accumulated by the former prosecutor across her decades in public life, as she rose from San Francisco district attorney, to attorney general of California, and then to become the state’s junior senator. In Washington, she’s gained national attention for ruthless interrogations of Trump appointees, exchanges that helped cemented her status as a smart and no-nonsense rising star. Now, having been tapped by Joe Biden to be his running mate, Harris is undertaking a historic run for the White House.