The third annual 50 Over 50 list might be our most powerful list yet: This collection of founders, innovators and creators have a sphere of influence that stretches from the deep sea to outer space—literally.

Sixty-three-year-old astronaut Peggy Whitson made history this spring when she became the first woman to command a private mission to the International Space Station. Monica Jain, now 60, founded Fish 2.0 Ventures in 2012 and has facilitated some $400 million to entrepreneurs working to protect the world’s oceans and marine life. And for every earthling in between, Caryn Seidman-Becker, Patti LaBelle and Valerie Griffith are building brands (Clear Secure, Patti’s Good Life and SkinnyDipped, respectively) consumed by millions.

These are just five of the 200 fresh faces on the 2023 50 Over 50, but their breakthroughs, inventions and achievements represent this entire Forbes list. Produced in partnership with Mika Brzezinski and her Know Your Value Initiative and first launched in 2021, the 50 Over 50 highlights women doing their most innovative, impactful work at 50, 60, 70 and beyond.

The list is divided into four broad categories—innovation, impact, investment and lifestyle—and dozens of sub-sectors, including real estate, cryptocurrency, biotechnology and dance.

The 2023 edition stands out for the number of founders and owners amid its ranks: nearly half of the 200 women in this year’s collection have either founded or own their business, the highest-ever proportion of founders we’ve seen in three years.

Some have even founded multiple companies: Mariam Naficy, 52, founded eve.com in 1998 and sold it for $100 million in cash two weeks before the Nasdaq crashed in 2000. She started art and design marketplace Minted in 2007, grew it into a $300 million business and then, in 2021, started Heretic Ventures to invest in AI-driven companies. Chemist Carolyn Bertozzi, 56, has founded or cofounded eight businesses over her career—and if that doesn’t sound productive enough, she won the Nobel Prize for chemistry in 2022.

Naficy, Bertozzi and their compatriots were chosen for the final list in a five-month research, reporting, vetting and judging process. We start by opening nominations to the general public—an exercise that has resulted in thousands of nominations over the last three years—and solicit the Know Your Value team and Forbes journalists for insights into the women who are the most impactful people on their beats.

Read the full story on Forbes: https://www.forbes.com/50over50/

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