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Beat your Genes - Podcast

Neural adaptation or sensory adaptation is a gradual decrease over time in the responsiveness of the sensory system to a constant stimulus.

Hashimoto's disease, is an autoimmune disease in which the thyroid gland is gradually destroyed.

Fasting is the willing abstinence or reduction from some or all food, drink, or both, for a period of time. An absolute fast or dry fasting is normally defined as abstinence from all food and liquid for a defined period. Other fasts may be partially restrictive, limiting only particular foods or substances, or be intermittent.

Hypertension, also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure typically does not cause symptoms.Long-term high blood pressure, however, is a major risk factor for coronary artery disease, stroke, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia.

Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time.

Conditions to not fast:

Already emaciated.
Chronic Kidney Disease (depressed GFR)
Currently pregnant


The Rice Diet started as a radical treatment for malignant hypertension before the advent of antihypertensive drugs; the original diet included strict dietary restriction and hospitalization for monitoring.


Homeostasis
In biology, the state of steady internal physical and chemical conditions maintained by living systems. This dynamic state of equilibrium is the condition of optimal functioning for the organism and includes many variables, such as body temperature and fluid balance, being kept within certain pre-set limits (homeostatic range).

Rapid eye movement sleep (REM sleep or REMS)
unique phase of sleep in mammals and birds, distinguishable by random/rapid movement of the eyes, accompanied with low muscle tone throughout the body, and the propensity of the sleeper to dream vividly.

Half-life
Time required for a quantity to reduce to half of its initial value. The term is commonly used in nuclear physics to describe how quickly unstable atoms undergo, or how long stable atoms survive, radioactive decay.

Sleep deprivation
Condition of not having enough sleep. It can be either chronic or acute and may vary widely in severity.

Caffeine is a central nervous system (CNS) stimulant. Unlike many other psychoactive substances, it is legal and unregulated in nearly all parts of the world. There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptor and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system.

electrolyte
Substance that produces an electrically conducting solution when dissolved in a polar solvent, such as water. The dissolved electrolyte separates into cations and anions, which disperse uniformly through the solvent.

All known higher lifeforms require a subtle and complex electrolyte balance between the intracellular and extracellular environments. In particular, the maintenance of precise osmotic gradients of electrolytes is important. Such gradients affect and regulate the hydration of the body as well as blood pH, and are critical for nerve and muscle function.

The Pleasure Trap: Mastering the Hidden Force that Undermines Health & Happiness

by Douglas J. Lisle, Ph.D and Alan Goldhamer, D.C.

The authors point out that all of us, because of the Motivational Triad, are wired for self-sabotage until we get a firm handle on how these primitive drives specifically betray us in our daily lives, and then learn how to transcend their grip.

Ketosis is a metabolic state in which some of the body's energy supply comes from ketone bodies in the blood. Generally, ketosis occurs when the liver is metabolizing fatty acids or ethanol at a high rate in the absence of glucose and converting the product acetyl-CoA into ketone bodies.

Intermittent fasting is an umbrella term for various eating diet plans that cycle between a period of fasting and non-fasting over a defined period.