In the Outworld castle, Sindel secretly spoke with Shang Tsung on how Kitana was a fool for working alongside with Raiden. After her conversation ended, Kitana entered her room and Sindel falsely greeted her. When Shao Kahn was being tortured by two Shokans, Sindel killed them to rescue Shao Kahn. The two planned on dethroning Kitana. As Sheeva overheard the conversation, the two clashed, leading to Sheeva's defeat. More Shokans arrived and discovered Sheeva's unconscious body. Sindel pins the blame on Kitana, leading the Shokans to join her against Kitana to avenge Sheeva.

Geras, wearing new armor, confronts Sindel and the rejuvenated Shao Kahn in the Soul Chamber, and demands their services to Kronika. Feeling betrayed by Kronika due to Kitana gaining the Outworld throne, Shao Kahn refuses his services and instead decides to attack the construct with Sindel. Being defeated, Sindel knocks a weakened Geras away where Shao Kahn approaches and mercilessly beats a downed Geras over the head repeatedly with his Wrath Hammer, completely destroying his head with one final slam.

Shao Kahn and Sindel went on a mission to intervene in the battle between Raiden and Kronika's forces to seize the Hourglass for themselves. They defeated Sonya, Cassie, and past Johnny, seizing their ships that they were planning to take across the Sea of Blood. Dumping cargo to increase their speed, they caught up to Kitana Kahn's ship. While Kitana lost contact with the Shokan, Commander Cage, and the Special Forces, Kung Lao suspected Sindel's betrayal, but Kitana denies it. Kitana uses her scope to check the incoming fleet, only to discover Sindel's betrayal. In the keep, Kronika manipulate all Outworlders to fight against each other with the Hourglass.

Boarding the vessel, Shao Kahn brutally struck down Kotal, and Sindel defeated Jade. They fight Kung Lao, throwing him overboard after his defeat. Kitana pleaded her mother to stop the chaos and questioned what spell had Shao Kahn used on her. In reality, Sindel was never bewitched. She willingly married Shao Kahn. She explained why she betrayed Jerrod and to strengthen her bond with Shao Kahn, she helped him murdered her former husband. Much to Kitana's disgust, she clashed with her mother and was defeated. Shao Kahn clashed with Liu Kang and defeated him. He and Sindel then convinced all of Kitana's soldiers (Osh-Tekks and Tarkatans) that Kitana was the traitor and a bad leader. Sindel wanted Kitana to be put in chains to suffer the 'anguish of defeat'. With all of her soldiers betraying her, Kitana reached for Liu Kang's hand, only for Shao Kahn to crush it.