NASA's SpaceX Crew-5 mission will launch four astronauts onboard the Crew Dragon spacecraft "Endurance" to the International Space Station from SLC-39A at Kennedy Space Center. NASA astronauts Nicole Mann and Josh Cassada, along with Japan Aerospace Exploration Agency astronaut Koichi Wakata and Russian cosmonaut Anna Kikina will board Endurance early Wednesday morning atop a SpaceX Falcon 9 rocket with lift-off targeted for 12 p.m. ET.