Leonard Hofstadter and Sheldon Cooper are both brilliant physicists working at Cal Tech in Pasadena, California. They are colleagues, best friends, and roommates, although in all capacities their relationship is always tested primarily by Sheldon's regimented, deeply eccentric, and non-conventional ways.

They are also friends with their Cal Tech colleagues mechanical engineer Howard Wolowitz and astrophysicist Rajesh Koothrappali. The foursome spend their time working on their individual work projects, playing video games, watching science-fiction movies, or reading comic books.

Main Cast:

1.kaley cuoco as penny

2.jim parsons as sheldon cooper

3.johnny galecki as leonardo Hofstadter

4.mayim bialik as amy farrah

5.kunal nayyar as raj koothra

6.melissa rauch as bernadette

7.Simon Helberg as howard

8.Kevin Sussman as stuart bloom

9.John Ross Bowie as barry kripke

10.Sara Gilbert as leslie winkle

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