As Pennsylvania moves towards serious discussions about the legalization of marijuana, this event brought together subject matter experts, community leaders, clinicians, researchers, public health advocates and policy makers for a multifaceted discussion on ways to address the needs of our community and city as a whole. The esteemed panel of experts discussed how the marijuana legalization movement affects the social determinants of health, with a focus on marginalized groups and young people. The panel also discussed how to engage the community and advocate for racial and social justice appropriate responses to legalization, while balancing the challenges around youth access and injury prevention. The audience contributed insightful comments and questions to round out the discussion and look ahead at potential next steps.