In this episode, my guest is Dr. Michael Eisenberg, MD, a urologist and professor specializing in male sexual function and fertility at Stanford University. Based on his clinical work and research, he is considered a top world expert on male sexual and reproductive health. We discuss testosterone levels and what really impacts them, testosterone therapy, sperm quality and counts, penile and testicular health and function, pelvic floor and prostate and urinary tract health, erectile function and dysfunction and the various causes and treatments for common male sexual, hormonal and reproductive challenges. We also address post-finasteride syndrome and trends in penile length. This episode is rich in actionable information about men’s sexual and reproductive health, including key tests and at-home evaluations, and the behavioral, nutritional, exercise and prescription-based tools that can support male sexual and reproductive health.

Thank you to our sponsors
AG1: https://drinkag1.com/huberman
ROKA: https://roka.com/huberman
Eight Sleep: https://eightsleep.com/huberman
LMNT: https://drinklmnt.com/huberman
Momentous: https://livemomentous.com/huberman

Dr. Michael Eisenberg
Clinical profile: https://shc.is/3MwGvNL
Academic profile: https://stan.md/3QV7Njz
Publications: https://stan.md/3QKC1W1
Stanford Male Reproductive Medicine & Surgery Program: https://shc.is/3SAbbBg
X: https://twitter.com/drmeisenberg
LinkedIn: https://www.linkedin.com/in/michael-eisenberg-9230a429

Articles
Evidence for decreasing quality of semen during past 50 years: https://bit.ly/465P8Wm
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries: https://bit.ly/3FMzlB9
Geographic differences in semen quality of fertile U.S. males: https://bit.ly/463SxoF
Self-rated health and semen quality among 3,457 young Danish men: https://bit.ly/461q4j6
Effect of Radiation Emitted by Wireless Devices on Male Reproductive Hormones: A Systematic Review: https://bit.ly/46XON9C
The influence of direct mobile phone radiation on sperm quality: https://bit.ly/3tUdG7i
Cannabis and Male Fertility: A Systematic Review: https://bit.ly/46QubQt
Association of paternal age with perinatal outcomes between 2007 and 2016 in the United States: population based cohort study: https://bit.ly/3QiJ4UE
Worldwide Temporal Trends in Penile Length: A Systematic Review and Meta-Analysis: https://bit.ly/40s7UGi

Other Resources
Testosterone trends: https://www.urologytimes.com/view/testosterone-levels-show-steady-decrease-among-young-us-men

Huberman Lab Episodes Mentioned
The Science of How to Optimize Testosterone & Estrogen: https://www.hubermanlab.com/episode/the-science-of-how-to-optimize-testosterone-and-estrogen

The Science of Healthy Hair, Hair Loss and How to Regrow Hair: https://www.hubermanlab.com/episode/the-science-of-healthy-hair-hair-loss-and-how-to-regrow-hair

Timestamps
00:00:00 Dr. Michael Eisenberg
00:01:49 Sponsors: ROKA & Eight Sleep
00:04:20 Sperm Quality, Geographic & Environmental Factors
00:12:00 Fertility & Sperm Quality; Testosterone, Cell Phones & Heat
00:19:26 Testosterone, Age, Obesity
00:26:49 Tool: Optimize Sperm Quality, Exogenous Testosterone, hCG
00:35:26 Sponsor: AG1
00:36:57 Tool: Lifestyle Factors & Sperm Quality, Alcohol
00:43:27 Sperm Quality, Recreational & Over-the-Counter Drugs, Cannabis
00:46:56 High-Impact Sports, Traumatic Brain Injury (TBI), Pituitary & Testosterone
00:49:55 Bicycling, Numbness & Sexual Dysfunction; Walking & Testosterone
00:55:39 Exogenous Testosterone Therapy & Cancer
00:58:39 Sponsor: LMNT
00:59:57 Sexual & Urinary Health, Nighttime Urination
01:03:12 Sleep & Semen Quality; Overall Health
01:09:19 Tool: Sperm Analysis & Overall Health; Sperm Banking
01:13:21 Paternal Age & Puberty Trends; Older Fathers & Child Health Risk
01:26:42 Tool: Prostate Health, Urination; Tadalafil (Cialis)
01:33:02 Urinary Tract Infections (UTIs); Erectile Dysfunction Causes
01:38:21 Blood Flow & Erectile Dysfunction, Medication; Cardiovascular Health
01:44:30 Mechanical Erectile Dysfunction Treatments; Peptides; Delayed Ejaculation
01:52:36 Pelvic Floor Health, Urology & Physical Therapy; Split-Stream Urination
01:59:03 Penile Length & Trends; Dihydrotestosterone (DHT), Puberty
02:09:01 Hair Loss, Dutasteride, Finasteride & Sexual Health; Post-Finasteride Syndrome
02:16:11 Clomiphene, Testosterone & Estrogen Signaling
02:19:31 Follicle-Stimulating Hormone (FSH) Therapy; Prolactin, Estrogen
02:24:15 Varicocele; Peyronie’s Disease
02:27:26 Testis & Cancer Risk; Insurance, Blood Profiles & Semen Analysis
02:35:03 Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter

#HubermanLab #Science #MaleFertility

Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com

Disclaimer: https://www.hubermanlab.com/disclaimer