Title:
Space and memory: insights from intracranial recordings in freely-moving humans

Abstract:
Little is known of the underlying mechanisms in the human brain that allow one to keep track of their own location or that of others while freely moving. I will present on recent findings from our research platforms that allow for wireless recording of deep brain activity in human participants that are able to freely maneuver while in real or virtual spatial environments. We find that specific patterns of human medial temporal lobe activity are modulated by eye movements, position, walking direction, memory, task goal and the presence of others. Lastly, I will present updates on our ongoing aim to use mobile deep brain recording in multiple interacting participants navigating augmented or real-world environments.