Jess Hilarious got cancelled on TikTok after addressing a trans woman who said females do not own periods or womanhood. They said women are not the "gatekeepers of periods or womanhood". This sparked outrage and comedian Jess Hilarious responded asking who is going to protect women.

TS Maddison also got involved in the debate and has now fallen out with blogger Tasha K, who sided with Jess Hilarious. Other people to defend Jess include fellow comedian Corey Holcomb. The hashtag #canceljesshilarious was prevalent on TikTok as many trans women came for her.