About the guest: Robert Lustig, MD is a physician-researcher and expert of metabolic health. He is Professor emeritus of Pediatrics, Division of Endocrinology at the University of California, San Francisco (UCSF), specializing in neuroendocrinology with an emphasis on the regulation of energy balance by the central nervous system. His research and clinical practice has focused on childhood obesity and diabetes.

Episode summary: Nick and Dr. Lustig discuss the true causes of obesity and metabolic discussion; how the in utero environment during pregnancy leads to multigenerational effects on health; different forms of sugar like fructose vs. glucose; different dietary fats like omega-6 and omega-3 PUFAs, and saturated fat; oxidative stress & mitochondria biology; how temperature, altitude & oxygen affect obesity; processed foods and how industry influences public perception; body positivity & public education; insulin, diabetes & fatty liver disease; statins & cardiovascular health; and more.

*My content is never meant to serve as medical advice.

More content on the science of diet & metabolism:
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ABOUT Nick Jikomes:
Nick is a neuroscientist and podcast host. He is currently Director of Science & Innovation at a technology startup in the legal cannabis industry. He received a Ph.D. in Neuroscience from Harvard University and a B.S. in Genetics from the University of Wisconsin-Madison.

#metabolism #fasting #science #biology #medicine #food #health #exercise #stress #podcast #obesity #diabetes #fat #sugar #disease #inflammation

0:00:25 Intro
0:05:21 Placenta's role in fetal development & exposure to environmental toxins
0:10:20 Fructose & obesity
0:16:21 The browning reaction and its impact on health.
0:21:16 Fructose and glucose metabolism, addiction & obesity
0:26:40 Omega-6 fatty acids & health.
0:33:04 Saturated fats
0:39:00 Saturated fat & cardiovascular health
0:46:56 Statins
0:52:11 Diet & growth, with a focus on type 2 diabetes and statins
0:58:31 Food & obesogens, with a focus on fruit & diabetes
1:02:40 Obesogens in the environment
1:07:18 Environmental toxins & Estrogens
1:12:47 Nutrition & health
1:21:01 Obesity & the unholy alliance of special interests
1:25:51 Improving school meals & education
1:32:05 Limitations of energy balance model of obesity
1:36:43 The role of calories in weight gain and health
1:43:07 Insulin & weight gain in children with brain tumors
1:46:55 Obesity & energy metabolism, with a focus on reactive oxygen species and mitochondria
1:53:49 Mitochondria and metabolic health