Management of COVID-19-related respiratory failure differs from what is necessary for ARDS. Rather than having alveolar edema, COVID-19 patients have pulmonary vascular dysregulation. Gas exchange is severely compromised with little reduction in lung compliance. Ventilatory support for COVID-19 patients requires higher than normal tidal volumes with minimal PEEP and allowance for higher than usual serum CO2 levels. How the unique pathophysiology of respiratory failure should be treated is discussed by John J. Marini, MD, professor of medicine at the University of Minnesota.

Read the JAMA Insights article co-authored by Dr Marini here: https://ja.ma/2Y3N7KP

• Earn Free CME credits by watching JAMA Livestreams and completing a brief questionnaire. Claim 0.5 credits for each video at https://ja.ma/covidqa
• Coronavirus Resource page from the JAMA Network: https://ja.ma/covidyt

#Coronavirus #COVID19 #SARSCoV2
---------------------------------------------------------------------------------
For more from JAMA
• https://www.jama.com
• https://www.facebook.com/JAMAJournal
• https://www.twitter.com/JAMA_Current
• https://www.linkedin.com/company/jamanetwork

Follow the #JAMANetwork
• https://www.jamanetwork.com
• https://www.facebook.com/JAMANetwork
• https://www.twitter.com/JAMANetwork
• https://www.instagram.com/JAMANetwork
• https://www.pinterest.com/JAMANetwork