Dr David Sinclair is sharing his view on NMN vs NR, metformin, his personal experinece on NAD IV therapy. NMN & NR are both NAD+ precursors. NAD IV therapy is a type of intravenous treatment which is claimed to be able to stimulate cell regeneration in your body. Metformin is a derivative of a natural molecule called a “biguanide,” from a flower called French lilac. It has been used as an herbal medicine in Europe for centuries. A study of more than 41,000 metformin users between the ages of 68 and 81 concluded that metformin reduced the likelihood of dementia, cardiovascular disease, cancer, frailty, and depression.
Metformin Article By Dr David Sinclair https://lifespanbook.com/metformin-pill/
NMN & NR Article By Dr David Sinclair https://lifespanbook.com/nad-boosters/
Differential effects of metformin on age related comorbidities in older men with type 2 diabetes
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5654524/

Dr David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

Dr Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.

Dr Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.
He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time's Top 50 in healthcare in 2018.

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