The U.S. is currently in the throes of a major opioid epidemic, but how can we come out of it? Dr. Dan Ciccarone, professor and physician at UCSF, describes his interdisciplinary research, including street-level interviews with drug users, to offer a broader context for the epidemic as well as ways to address it. Dr. Dan Ciccarone, MD, MPH is a Professor in the Department of Family & Community Medicine at the University of California, San Francisco. His population-based studies, utilizing both quantitative and qualitative methodologies, aim to deepen our understanding of HIV and related disease and risk-taking among socially marginalized groups. He is currently leading the Heroin in Transition study with its integrated multidisciplinary — ethnographic, economic and statistical modeling — aims to examine the recent rise in heroin use and the expanding diversity of heroin source-forms and illicitly-made synthetic opioids (e.g. fentanyls) and their relationship to sharp increases in illicit opioid-involved mortality and morbidity. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx