You can easily fix Excel file blank issue by using Stellar Repair for Excel software. Read this blog: https://www.stellarinfo.com/blog/excel-2016-opening-blank-workbook/

Start Microsoft Excel.
Select File -- Options.
Switch to the Advanced section.
Locate the General group of preferences on the page that opens. You find it near the end of the page.
Make sure that "Ignore other applications that use Dynamic Data Exchange (DDE) is not checked. If it is, remove the checkmark and select ok.

This is another option that is easy to check.

Select File -- Options.
Load the Advanced options page.
Scroll down until you come to the Display Group. Locate "disable hardware graphics acceleration", and check the preference.

Microsoft Office comes with two repair options. The first runs a local (quick) repair attempt, the second an online repair. Please note that you may be asked to re-enter the Office product ID and authenticate the product again if you run an online Office repair.

I suggest you start with the quick repair and see if it resolves the document loading issue in Excel. If it does not, you may try the online repair option, but remember to have your product key at hand when you do as you may need it.